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Sherry Huang, M.D.

Education:

1990-1994   Albert Einstein College of Medicine, The Bronx, NY
Degree:  M.D.

1986-1990   Massachusetts Institute of Technology, Cambridge, MA
Degree: S.B., Chemistry, Minor in English Literature

Academic Appointments:

2000-present  Assistant Professor, UCSD Department of Pediatrics,
Division of Pediatric Gastreoenterology and Nutrition

Postdoctoral Training:

1997-2000   Fellowship in Pediatric Gastroenterology & Nutrition
University of California, San Diego Medical Center
Chief:  Joel E. Lavine, M.D., PhD.

1995-1997   Residency in Pediatrics
University of California, San Diego Medical Center
Chair:  Stanley Mendoza, M.D.

1994-1995   Internship in Pediatrics
University of California, San Diego Medical Center

Postdoctoral Research:

1999-2000   Fellow, Pediatric Gastroenterology and Nutrition
Laboratories of C. Richard Boland, M.D. and John M Carethers, M.D.

1998-1999   Postdoctoral Research Training Program
Department of Medicine, Division of Gastroenterology
University of California, San Diego 
Director:  Martin Kagnoff, M.D.

Grand Support:

Active: Extramural
Foundation for Digestive Health and Nutrition, Research Scholar Award, “Pathogenesis of Familial Juvenile Polyposis”, 7/1/02-6/30/05 PI: Sherry C. Huang, M.D. ($195,000 total direct costs)

NIDDK (HD97549-01), KO8 Award, “Pathogenesis of Familial Juvenile
Polyposis”, 9/30/02-8/31/07 PI: Sherry C. Huang, M.D. ($538,750 total direct
costs)

NIH NIDDK LRP: 09/01/03-09/01/05: $16,250 direct funds to pay back
educational loans for PI Sherry C. Huang, M.D.

Past
American Digestive Health Foundation, Astra Merck Fellowship/Faculty
Transition Award; “Analysis of TGFB1 Signal Transduction Genes in Colon
Cancer-Prone Hamartomatous Polyposis Syndromes”, 7/1/99-6/30/01 PI: C.
Richard Boland, M.D. ($72,000 total direct costs).

NIDDK (DK070202-22), National Research Service Award to Sherry C. Huang, M.D., 6/98-6/99.

Certification and Licensure:

Certification - American Board of Pediatrics, Subspecialty of Gastroenterology & Nutrition 2003
Diplomate, American Board of Pediatrics, 1999
Physician License, State of California, 1995
Diplomate, National Board of Medical Examiners, 1995

Honors and Awards:

2003       NIH Young Investigators Travel Award
2002       FDHN Research Scholar Award
2002       National Center for Leadership & Academic Medicine Participant, UCSD School of Medicine
1998       AGA Fellow to Faculty Transition Award
1997       American Academy of Pediatrics Certificate of Achievment
1988-90  Phi Lambda Upsilon, Chemistry Honor Society, Massachusetts Institute of Technology
1988-90  Outstanding College Students of America
1987       Westinghouse Scholarship
1986       Junior Science and Humanities Scholar, U.S. Dept of Agriculture
1986       "Most Valuable Student", Elks Club Scholarship
1985       Japan-US Senate Scholar (US Senator Paul Laxalt)

Affilications:

Childrens Specialist Academic Affairs Research Committee, 2001-present
Childrens Hospital San Diego Interdisciplinary Allied Health Professional
Committee
UCSD Quality Assurance, 1997-2000
North American Society for Pediatric Gastroenterology and Nutrition, 2001
Gastroenterology Research Group, 1998-present
MIT Educational Counselor, 1997-present
American Gastroenterology Association, 1996-present
American Academy of Pediatrics, 1994-present

Teaching Activities:

Medical Student Teaching (UCSD)
  • SOM 206 GI Physiology Conference I and II, February, 1999
  • SOM 206 GI Physiology Conference IV, March, 2000
  • SOM 206 GI Physiology Conference I, March 2001
  • SOM 206 GI Physiology Conference III and IV, March 2002
  • SOM 206 GI Physiology Conference I-IV, March 2003
  • SOM 206 GI Physiology Conference I-IV, March 2004

Resident Teaching
  • July 2002, September, February 2003- Second Year Teaching Attending
  • Director, Pediatric GI & Nutrition Didatic Course-2003 to current

Student Mentorship
  • Jeffrey Lee, MSII-ISP mentor
  • Sabrina Yan, MSI-student advisor
  • Andrea Lee, MSIV-student advisor
  • Emily Wang, MD (PL2)-faculty mentor

University Service

  • Search Committee: Dept of Pediatrics, Division of Gastroenterology
  • Search Committee: Dept of Pediatrics/School of Pharmacy, Division Chief of Pediatric Pharmaco-biology.
  • San Diego Export Committee

Presentations:

  1. UCSD Dept. of Pediatrics Grand Rounds, "Clinical Pathologic Correlation", August, 1996.
  2. UCSD Dept. of Pediatrics Resident Core Lecture, "Constipation", September, 1997.
  3. UCSD Dept. of Medicine, Combined GI/ Surgery Grand Rounds, "Molecular Genetics of Juvenile Polyposis Coli", October, 1997.
  4. UCSD Dept. of Pediatrics, Chief Rounds, "Hypoalbuminemia in an Adolescent Girl", November, 1997.
  5. UCSD Dept. of Medicine, GI Pathology Rounds, "Juvenile Polyposis", November, 1997.
  6. Children's Hospital and Health Center, Pediatric Intensive Care Core Lecture", Liver Transplantation in the ICU Setting", March, 1998.
  7. Scripps Mercy Hospital, Dept. of Pediatrics Grand Rounds, "Helicobacter Pylori Infection in the Pediatric Population", May 1998.
  8. UCSD Dept. of Medicine, GI Pathology Rounds, "Biliary Atresia", May 1998.
  9. UCSD Dept. of Medicine, Combined GI/Surgery Grand Rounds, "Molecular Genetics of Hirschprung's Disease", December 1998.
  10. UCSD Dept. of Medicine, GI Fellow's Conference, "Pediatric Liver Diseases", December, 1998.
  11. UCSD Dept. of Pediactrics Chief Rounds, "Hirschprung's Disease", December, 1998.
  12. UCSD Dept. of Pediatrics PACE Educational Program, "Hirschprung's Disease", April, 1999.
  13. UCSD Dept. of Medicine, GI Fellow's Conference, "Molecular Genetics of Familial Cholestasis", March, 2000.
  14. UCSD Dept. of Pediatrics Chief Rounds, "Molecular Genetics of Juvenile Polyposis Syndrome", April, 2000.
  15. Dept. of Pediatrics Grand Rounds, US Naval Center, San Diego, “GERD”, October, 2001
  16. UCSD Dept. of Pediatric GI Teaching Conference, “Polyposis Syndromes”, September, 2002
  17. DDW, 2003 Orlando, FL. Pediatric GI Research Symposium, “The mismatch repair (MMR) protein hMSH3 is lost from polyp epithelium of patients with PTEN germline hamartomatous syndromes.”, May 2003.
  18. Children’s Hospital San Diego Brown Bag Lunch Seminar, “GI Bleeding”, February 2004
  19. Childrens Hospital San Diego, Mini GI CME Seminar, “Food Allergies”, March 2004.
  20. DDW, 2004 New Orleans, LA. Genomic Instability Research Symposium, “PTEN is Frameshift-Mutated in hMSH3- as well as hMLH1-Deficient Backgrounds”, May 2004.
  21. Children’s Hospital San Diego, Grand Rounds “CPC-Allergic Enteropathy”, June 2004.
  22. Physician in Chief Grand Rounds, UCSD Dept of Pediatrics “New Genes in Polyposis Syndrome”, November 2004.

Publications:

Manuscripts

  1. Huang SC, Chen CR, Lavine JE, Taylor SF, Newbury RO, Pham T-TT, Ricciardiello L, Carethers JM. Genetic heterogeniety in familial juvenile polyposis. Cancer Res 2000: 60 (24) 6882-5
  2. Huang SC, Lavine JL, Boland PS, Newbury RO, Kolodner R, Pham TT, Boland CR, Carethers JM. Germline Characterization of Early-Aged Onset HNPCC. J of Pediatrics 2001:138 (5):629-35.
  3. Firoino A, Huang SC, Carethers JM. Role of the PTEN tumor suppressor gene in sporadic cancer and inherited hamaratomatous syndromes. Recent Res. Devel Cancer, 3(2001): 309-336.

Chapters

Huang SC, Carethers JM. Hamartomatous Polyposis Syndromes. Encylcopedia Gastroenterology. Nov, 2003. Encyclopedia of Gastroenterology, Academic Press, Elsevier Science.

Abstracts

  1. Huang S, Lavine JE. Efficacy of Sumatriptan in aborting attacks of cyclic vomiting. Gastroenterology 112 (4):A751, 1997. (Poster presentation at the annual meeting of the American Gastroenterological Association, May 1997,
    Washington, D.C.).
  2. Huang SC, Pham T-TT, Zigman, AF, Lavine JE, Hones MC, Boland CR, Carethers JM. Absence of germline SMAD4 mutations in three Bannayan-Riley-Ruvalcaba syndrome patients with wild-type PTEN. Gastroenterology 116:A543 (G2384), 1999. (Poster presentation at the annual meeting of the American Gastroenterological Association, May 1999, Orlando FL).
  3. Carethers JM, Pham T-TT, Huang SC. Recognition of alkylating-induced mutations by the DNA mismatch repair system prevents activation of the cyclin bcdc2 complex. Gastroenterology 116:A384 (G1683), 1999.
  4. Huang SC, Chen CR, Pham TTT, Lavine JE, Taylor SF, Newbury RO, Carethers JM. True association of germline PTEN mutation with juvenile polyposis syndrome. Gastroenterology 118: May 2000 (Poster presentation at the annual meeting of the American Gastroenterological Association, May 2000, San Diego, CA).
  5. Carethers JM, Doctolero RT, Lopez BM, Alonso JC, Huang SC, Pham TTT. Dinucleotide, but not mononucleotide microsatellite instability, is present in familial juvenile polyps. Gastroenterology 118: May 2000.
  6. Huang SC, Lavine JE, Boland PS, Kolodner R, Newbury RO, Boland CR, Carethers JM. Germline characterization of early-aged onset of HNPCC. Gastroenterology 118: May 2000 (Oral presentation at the annual meeting of the American Gastroenterological Association, May 2000, San Diego, CA).
  7. Huang SC, Smith EJ, Fiorino A, Newbury Ro, Carethers JM. Loss of PTEN and hMSH3 protein expression from familial juvenile polyp epithelium. Gastroenterology 120: 2001. (Poster presentation at the annual meeting of the American Gastroenterological Association, May 2001, Atlanta, GA).
  8. Baun MB, Doctolero RT, Huang SC, Goel A, Cabrera BL, Smith EJ, Fiorino A, Carethers JM. Mutations of the Tumor Suppressor gene PTEN in microsatellite unstable colorectal cancer. Gastroenterology 122:4: Supplement, May 2002.
  9. Huang SC, Swaminath A, Smith EJ, Docotlero RT, Dreilinger A, Carethers JM. The mismatch repair (MMR) protein hMSH3 is lost from polyp epithelium of patients with PTEN germline hamartomatous syndromes. Gastroenterology124:4 Supplement, May 2003. (Oral presentation at the annual meeting of the American Gastroenterological Association, May 2003, Orlando, FL).
  10. Tajima A, Cabrera BL, McMahon H, Doctolero RT, Huang, SC, Carethers JM. The mismatch repair (MMR) complex hMUTSα recognizes 5-Fluorouracil (5FU) modified DNA: a mechanism for 5FU sensitivity. Gastroenterology124:4 Supplement, May 2003. (Oral presentation at the annual meeting of the American Gastroenterological Association, May 2003, Orlando, FL).
  11. Huang SC, E. Julieta Smith, Ryan T. Doctolero, Michelle Baun, John M. Carethers. PTEN is Frameshift-Mutated in hMSH3- as well as hMLH1-Deficient Backgrounds. Gastroenterology, May 126:4,2004. (Oral presentation at the annual meeting of the American Gastroenterological Association, May 2004, New Orleans, LA).
  12. J Kurland, S Beck, C Solomon, R Doctolero, O Brann, J Carethers, SC Huang. “Cyclooxygenase 2 is not overexpressed in polyps from Juvenile Polyposis Syndrome patients with mutant BMPR1A”, American College of Gastroenterology, P88, Ocotber 2004.
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