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Karen Kling, M.D.
OFFICE ADDRESS
Pediatric General and Transplant Surgery
Children’s Hospital of San Diego and UCSD
8010 Frost St. #414
San Diego, CA 92123
858-966-7711
APPOINTMENTS
2005 Assistant Professor, Pediatric General and Transplant Surgery
University of California, San Diego – School of Medicine
2004 Assistant Professor, Pediatric Surgery
Johns Hopkins Hospital
2002 Instructor, Pediatric Surgery
Johns Hopkins Hospital
2002 Instructor, Pediatric Transplant Surgery
Johns Hopkins Hospital
LICENSURE
- California Medical License 1994
- Federal DEA License 1994
- Maryland Medical License 2002
- Maryland Controlled Substances 2002
CERTIFICATION
American Board of Surgery 2001
General Surgery
American Board of Surgery 2004
Pediatric Surgery
CLINICAL TRAINING
Internship, General Surgery 1993-1994
University of California, Los Angeles
Residency, General Surgery 1994-2000
University of California, Los Angeles
Fellowship, Pediatric Surgery 2000-2002
Johns Hopkins/University of Maryland Program
Fellowship, Pediatric Transplant 2002-2003
Johns Hopkins Hospital
EDUCATION
BA Molecular Biology: Minor, Literature 1984-1988
University of California, San Diego
Doctor of Medicine 1989-1993
Johns Hopkins University School of Medicine
HONORS
- House staff appreciation award 2002
Johns Hopkins Department of Pediatrics
- Outstanding resident teacher award 2000
University of California, Los Angeles
Department of General Surgery
- Golden apple teaching award 2000
University of California, Los Angeles
Medical School
- Administrative chief resident 1999-2000
University of California, Los Angeles
Department of General Surgery
- SSAT/Ross research laboratories 1997
(Kling, Cole, Rigberg, Kim, McFadden. Clues of Chemotherapy Resistance)
- Pilot grant $5000 1996
Center of Ulcer Research
University of California, Los Angeles
(Kling, McFadden. Apoptosis and Gastrointestinal Malignancies)
Graduate
- Japanese Medical Society scholarships 1990-1992
- Johns Hopkins Alumni scholarships 1989-2993
Undergraduate
- Cum laude graduate 1988
University of California, San Diego
- University Scholarships 1984-1988
University of California, San Diego
- Provost’s honor list 1984-1988
University of California, San Diego
- Provincial Scholarship 1984
Province of British Columbia
- Forum for young Canadians 1984
Government student representative
- Senior academic champion/all subjects 1984
St. Margaret’s School
- Creative Writing Award 1978
St. Margaret’s School
Music
- Kowalchuk memorial choir award 1984
St. Margaret’s School
- Royal Conservatory of Music Certificate 1983
Toronto Conservatory of Music
- Winner Solo Baroque Piano 1981
Victoria Music Festival
- Solo Romantic Piano – 2nd 1981
Victoria Music Festival
- Winner solo piano 1975
Cornelia Overstreet award, Louisville, KY
Athletics
- Winner Coed-4 Venturers volleyball 1995
Manhattan Beach, CA
- Winner (female 18-24) 1992
Moonlight Madness biathlon
- AMSA volleyball champion 1991
PROFESSIONAL SOCIETIES
- Fellow, American College of Surgeons 2005
- International Pediatric Transplant Association 2003
- American Pediatric Surgery Association 2002
Candidate Member
- American College of Surgeons, Candidate 2000
- Longmire Surgical Society 1993
- Johns Hopkins Medical/Surgical Assn 1993
- Golden Key National Honor Society 1988
RESEARCH
Necrotizing enterocolitis and cytokines; 1995-1997
Gastrointestinal peptides, apoptosis,
and tumor suppression
UCLA Department of Surgery
Mentor: David McFadden, MD
Isolation of Heat Shock protein, 1986-1989
Cisplatin resistance
UCSD Cancer Center
San Diego, CA
Mentor: Robert Enns, PhD
Laser Doppler non-invasive technology 1985-1988
Non-invasive vascular laboratory
UCSD/VA Hospital
Mentor: Arnost Fronek, MD
PUBLICATIONS
Manuscripts
Kling, Lau, Colombani. Biliary complications of living related pediatric liver transplant patients. Pediatric Transplantation. 7: 1-7, 2003
Farooq, Kling, Yamini, Gelabert, Baker, Freischlag. Penetrating ulceration of the infrarenal aorta: case reports of an embolic and an asymptomatic lesion. Annals of Vascular Surgery. 15: 255-9, 2001
Beanes, Kling, Fonkalsrud, Torres, Salusky, Quinones-Baldrich, Atkinson. Surgical aspects of dialysis in newborns and infants weighing less than ten kilograms. Journal of Pediatric Surgery. 35: 1543-8, 2000
Kling, Applebaum, Dunn, Buchmiller, Atkinson. A novel technique for correction of intestinal atresia at the ligament of Treitz. Journal of Pediatric Surgery. 35: 353-5, 2000
Kim, Kling. A novel technique for correction of intestinal atresia at the ligament of Treitz. Comment. Journal of Pediatric Surgery. 35: 356, 2000
Kling, Kirby, Kwan, Kim, McFadden. Interleukiin-10 inhibits inducible nitric oxide synthase in an animal model of necrotizing enterocolitis. International Journal of Surgical Investigation. 1: 337-42, 2000
Kling, Kim, Cole, McFadden. B-cell leukemia protein-2 peptide YY chemotherapy resistance in colon cancer. American Journal of Surgery. 178: 411-4, 1999
Kling, Ostrzega, Schmit. Breast conservation after induction chemotherapy for locally advanced breast cancer. The American Surgeon. 63: 861-4, 1997
Kling, Rongione, Evans, McFadden. The Delorme procedure: a useful operation for complicated rectal prolapse in the elderly. The American Surgeon. 62: 857-60, 1996
Rongione, Evans, Kling, McFadden. Ductography is a useful technique in evaluation of abnormal nipple discharge. The American Surgeon. 62: 785-8, 1996
Katz, Vick, Kling, Andrews, Howell. Effect of topoisomerase modulators on cisplatin cytotoxicity in ovarian carcinoma cells. European Journal of Cancer. 26: 724-7, 1990
Published Abstracts
Kling, Conner, Lau, Colombani, Cuffari. Pharmacokinetic analysis of Mycophenolic acid levels in pediatric transplant patients. Pediatric Transplantation. 7s4: 46-132, 2003 abstract
Ugo, Kraus, Racusen, Haas, Burdick, Montgomery, Colombani, Lau, Paidas, Kling, Eustace, Zachary, Leffell, Reeb, Molmenti, Ratner, Samaniego, Rabb, Rodriquez-Reimunder, Molmenti. Outcome of cadaveric pediatric renal allografts according to early recipient creatinine values: extended and non-extended criteria organs. Transplantation supp. 74: 705, 2002 abstract 3455
Falta, Kraus, Ugo, Racusen, Haas, Burdick, Montgomery, Colombani, Lau, Paidas, Kling, Eustace, Zachary, Leffell, Reeb, Molmenti, Ratner, Samaniego, Rabb, Molmenti. Incidence of acute and chronic rejection in pediatric and adult cadaveric renal donors. Transplantation supp. 74: 705, 2002 abstract 3456
Kling, Kirby, Kim, McFadden. IL-10 decreases TNFa mRNA and protein in a necrotizing enterocolitis model. AAS program. 31: 142, 1997 abstract 89
Kling, Rongione, Kwan, Mai, McFadden. Bcl-2 overexpression is linked to pancreatic cancer resistance to chemotherapy. SSO Cancer Symposium. 50: 46, 1997 abstract 46
Rongione, Kling, Zinner, Newton, Ashley, McFadden. Intravenous growth factors stimulate glucose absorption through the luminal sodium/glucose cotransporter. Surgical Forum. 82: 180, 1996
Kling, Kwan, Menon, Rongione, Ashley, McFadden. Survival benefit in a neonatal rat model of necrotizing enterocolitis with IL-10. Gastroenterology. 110: 1996 abstract 812
Kling, Rongione, McFadden. Peptide YY growth inhibition of colon carcinoma. Gastroenterology. 110: 1996 abstract 543
Rongione, Newton, Zinner, Kling, Ashley, McFadden. Luminal growth factors enhance intestinal absorption of glucose, water, and electrolytes. Gastroenterology. 110: 1996 abstract 835
Dunn, Lane, Rongione, Kling, Newton, Zinner, McFadden, Ashley. Cholera toxin alters intestinal transport by neural mechanisms. Gastroenterology. 110: 1996 abstract 322
Book Chapters
Kling. Congenital Pulmonary Anomalies. In: Baumgartner W, Yuh D, Vricella, L. (eds) The Johns Hopkins Manual of Cardiothoracic Surgery. McGraw-Hill, New York : chapter ,
Kling. Soft Tissue Injuries. In: Nichols, Lappe, Paidas, Yaster, Schleien. (eds) Golden Hour: The Handbook of Advanced Pediatric Life Support. 3/e. Elsevier, Philadelphia : chapter ,
Kling. Pediatric Renal Transplantation. In: Oldham, Colombani, Foglia, Skinner. (eds) Surgery of Infants and Children. Lippincott Williams & Wilkins, Philadelphia 2004: chapter 47, 729-42
Kling, Colombani: Surgical management of congenital lesions of the lung. In: Franco, Putnam. (eds) Advanced Therapy in Thoracic Surgery. BC Decker Inc., Hamilton, ON :
Kling, Paidas. Constipation and Incontinence. In: Mattei. (ed) Surgical Directives: Pediatric Surgery. Lippincott Williams & Wilkins, Philadelphia 2002: 363-70
Presentations
Kling. Reduced Graft Techniques in Pediatric Liver Transplantation. Invited speaker, University of Maryland Department of Surgery Grand Rounds/CME symposium in Honor of J. Laurance Hill, Baltimore, MD, 6/23/05
Kling. Pediatric Transplantation. Invited speaker, Pediatric Grand Rounds – Greater Baltimore Medical Center, Towson, MD, 3/17/05
Kling. Pediatric Renal Transplantation. Invited speaker, Johns Hopkins Immunogenetics Group, Baltimore, MD, 11/29/04
Kling. Pediatric Liver and Kidney Transplantation. Invited Hopkins Pediatric ICU lecture. Baltimore, MD, 7/03
Kling, Lau, Colombani. Outcome of vascular reconstruction in pediatric living related liver transplantation. British Association of Paediatric Surgeons Annual Meeting, Estoril, Portugal, 7/03
Kling, Conner, Lau, Colombani, Cuffari. Pharmacokinetic analysis of Mycophenolic acid levels in pediatric transplant patients. International Pediatric Transplant Association 2nd Congress, Rio de Janeiro, Brazil, 4/03
Kling, Lau, Colombani. Biliary complications of living related pediatric transplant patients. International Pediatric Transplant Association 2nd Congress, Rio de Janeiro, Brazil, 4/03
Kling, Applebaum, Dunn, Buchmiller, Atkinson. Lateral Duodenectomy and Duodenostomy: a novel technique for jejunal atresia near the ligament of Treitz. invited vesalius.com presentation 11/99
Kling, Applebaum, Dunn, Buchmiller, Atkinson. Lateral Duodenectomy and duodenostomy: a novel technique for jejunal atresia near the ligament of Treitz. APSA, Rancho Mirage, CA 5/99
Kling, Kirby, Kim, McFadden. IL-10 decreases TNFa mRNA and protein in a necrotizing enterocolitis model. AAS, Dallas, TX 11/97
Rigberg, Cole, Kling, Kim, Lane, McFadden. p53 mutational status and chemoresistance in esophageal squamous cell carcinoma. VA Surgeons, Louisville, KY 8/97
Kling, Cole, Rigberg, Kim, McFadden. Peptide YY and apoptosis: clues to chemotherapy resistance and colon cancer. SSAT, Washington, DC 5/97
Kling, Kwan, McFadden. bcl-2 overexpression is linked to pancreatic cancer resistance to chemotherapy. SSO, Chicago, IL 3/97
Kling, Aharon, Thompson, Hiyama. Video assisted thoracoscopic surgery as primary treatment for spontaneous pneumothorax. Southern California ACS, Dana Point, CA 1/97
Kling, Schmit. Breast conservation after induction chemotherapy for locally advanced breast cancer. Southern California ACS, Dana Point, CA 1/97
Kling, Kwan, Rongione, Dunn, Ashley, McFadden. Interleukin-10 (IL-10) treatment decreases iNOS expression in a necrotizing enterocolitis model. AAS, Chicago, IL 11/96
Rongione, Kling, Zinner, Newton, Ashley, McFadden. Intravenous growth factors stimulate glucose absorption through the luminal sodium/glucose cotransporter. ACS, San Francisco, CA 10/96
Kling, McFadden. Peptide YY and its analogs in gastrointestinal malignancies. Gut Hormones. Florissant, CO 7/96
Kling, Kwan, Menon, Rongione, Ashley, McFadden. Survival benefit in a neonatal rat model of necrotizing enterocolitis with IL-10. AGA, San Francisco, CA 5/96
Dunn, Lane, Rongione, Kling, Newton, Zinner, McFadden, Ashley. Cholera toxin alters intestinal transport by neural mechanisms. AGA, San Francisco, CA 5/96
Rongione, Newton, Zinner, Kling, Ashley, McFadden. Luminal growth factors enhance intestinal absorption of glucose, water, and electrolytes. AGA, San Francisco, CA 5/96
Kling, Mai, Kwan, Newton, Rongione, Ashley, McFadden. PYY inhibits growth of human colon carcinoma in vitro. Longmire Visiting lecture and research day, Los Angeles, CA 3/96
Kling, Rongione, Newton, Ashley, McFadden. Short chain fatty acids mediate intestinal absorption. SUS, Washington, DC 2/96
Kling, Rongione, Evans, McFadden. The Delorme procedure: a useful operation for complicated rectal prolapse in the elderly. Southern California ACS, Santa Barbara, CA 1/96
Rongione, Evans, Kling, McFadden. Ductography is a useful technique in evaluation of abnormal nipple discharge. Southern California ACS, Santa Barbara, CA 1/96
Rongione, Kling, Evans, Ashley, McFadden. Peptide YY: A novel treatment for breast cancer. Southern California ACS, Santa Barbara, CA 1/96
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