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Karen Kling, M.D.

OFFICE ADDRESS

Pediatric General and Transplant Surgery
Children’s Hospital of San Diego and UCSD
8010 Frost St.  #414
San Diego, CA   92123
858-966-7711

APPOINTMENTS

2005   Assistant Professor,  Pediatric General and Transplant Surgery
University of California, San Diego – School of Medicine

2004   Assistant Professor, Pediatric Surgery
Johns Hopkins Hospital

2002   Instructor, Pediatric Surgery
Johns Hopkins Hospital

2002   Instructor, Pediatric Transplant Surgery
Johns Hopkins Hospital

LICENSURE

  • California Medical License   1994
  • Federal DEA License   1994
  • Maryland Medical License   2002
  • Maryland Controlled Substances   2002

CERTIFICATION

American Board of Surgery   2001
General Surgery

American Board of Surgery    2004
Pediatric Surgery

CLINICAL TRAINING

Internship, General Surgery   1993-1994
University of California, Los Angeles

Residency, General Surgery   1994-2000
University of California, Los Angeles

Fellowship, Pediatric Surgery   2000-2002
Johns Hopkins/University of Maryland Program

Fellowship, Pediatric Transplant   2002-2003
Johns Hopkins Hospital

EDUCATION

BA Molecular Biology:  Minor, Literature   1984-1988
University of California, San Diego

Doctor of Medicine 1989-1993
Johns Hopkins University School of Medicine

HONORS

  • House staff appreciation award   2002
      Johns Hopkins Department of Pediatrics
  • Outstanding resident teacher award   2000
      University of California, Los Angeles
      Department of General Surgery
  • Golden apple teaching award   2000
      University of California, Los Angeles
      Medical School
  • Administrative chief resident  1999-2000
      University of California, Los Angeles
      Department of General Surgery
  • SSAT/Ross research laboratories   1997
      (Kling, Cole, Rigberg, Kim, McFadden. Clues of Chemotherapy Resistance)
  • Pilot grant $5000   1996
      Center of Ulcer Research
      University of California, Los Angeles
      (Kling, McFadden.  Apoptosis and Gastrointestinal Malignancies)

Graduate

  • Japanese Medical Society scholarships  1990-1992
  • Johns Hopkins Alumni scholarships  1989-2993

Undergraduate

  • Cum laude graduate  1988
    University of California, San Diego
  • University Scholarships  1984-1988
    University of California, San Diego
  • Provost’s honor list   1984-1988
    University of California, San Diego
  • Provincial Scholarship  1984
    Province of British Columbia
  • Forum for young Canadians  1984
    Government student representative
  • Senior academic champion/all subjects  1984
    St. Margaret’s School
  • Creative Writing Award   1978
    St. Margaret’s School

Music 

  • Kowalchuk memorial choir award   1984
    St. Margaret’s School
  • Royal Conservatory of Music Certificate  1983
    Toronto Conservatory of Music
  • Winner Solo Baroque Piano   1981
    Victoria Music Festival
  • Solo Romantic Piano – 2nd   1981
    Victoria Music Festival
  • Winner solo piano   1975
    Cornelia Overstreet award, Louisville, KY

Athletics

  • Winner Coed-4 Venturers volleyball   1995
    Manhattan Beach, CA
  • Winner (female 18-24)   1992
    Moonlight Madness biathlon
  • AMSA volleyball champion   1991

PROFESSIONAL SOCIETIES

  • Fellow, American College of Surgeons   2005
  • International Pediatric Transplant Association   2003
  • American Pediatric Surgery Association   2002
      Candidate Member
  • American College of Surgeons, Candidate   2000
  • Longmire Surgical Society   1993
  • Johns Hopkins Medical/Surgical Assn   1993
  • Golden Key National Honor Society   1988

RESEARCH

Necrotizing enterocolitis and cytokines; 1995-1997
 Gastrointestinal peptides, apoptosis,
 and tumor suppression
 UCLA Department of Surgery
 Mentor:  David McFadden, MD

Isolation of Heat Shock protein, 1986-1989
 Cisplatin resistance
 UCSD Cancer Center
 San Diego, CA
 Mentor:  Robert Enns, PhD

Laser Doppler non-invasive technology 1985-1988
 Non-invasive vascular laboratory
 UCSD/VA Hospital
 Mentor:  Arnost Fronek, MD

PUBLICATIONS

Manuscripts

Kling, Lau, Colombani.  Biliary complications of living related pediatric liver transplant patients. Pediatric Transplantation.  7:  1-7, 2003

Farooq, Kling, Yamini, Gelabert, Baker, Freischlag.  Penetrating ulceration of the infrarenal aorta: case reports of an embolic and an asymptomatic lesion.  Annals of Vascular Surgery.  15:  255-9, 2001

Beanes, Kling, Fonkalsrud, Torres, Salusky, Quinones-Baldrich, Atkinson.  Surgical aspects of dialysis in newborns and infants weighing less than ten kilograms.  Journal of Pediatric Surgery.  35:  1543-8, 2000

Kling, Applebaum, Dunn, Buchmiller, Atkinson.  A novel technique for correction of intestinal atresia at the ligament of Treitz.  Journal of Pediatric Surgery.  35:  353-5, 2000

Kim, Kling.  A novel technique for correction of intestinal atresia at the ligament of Treitz.  Comment.  Journal of Pediatric Surgery.  35:  356, 2000

Kling, Kirby, Kwan, Kim, McFadden.  Interleukiin-10 inhibits inducible nitric oxide synthase in an animal model of necrotizing enterocolitis.  International Journal of Surgical Investigation.  1:  337-42, 2000

Kling, Kim, Cole, McFadden.  B-cell leukemia protein-2 peptide YY chemotherapy resistance in colon cancer.  American Journal of Surgery.  178:  411-4, 1999

Kling, Ostrzega, Schmit.  Breast conservation after induction chemotherapy for locally advanced breast cancer.  The American Surgeon.  63:  861-4, 1997

Kling, Rongione, Evans, McFadden.  The Delorme procedure:  a useful operation for complicated rectal prolapse in the elderly.  The American Surgeon.  62:  857-60, 1996

Rongione, Evans, Kling, McFadden.  Ductography is a useful technique in evaluation of abnormal nipple discharge.  The American Surgeon.  62:  785-8, 1996

Katz, Vick, Kling, Andrews, Howell.  Effect of topoisomerase modulators on cisplatin cytotoxicity in ovarian carcinoma cells.  European Journal of Cancer.  26:  724-7, 1990 

Published Abstracts

Kling, Conner, Lau, Colombani, Cuffari.  Pharmacokinetic analysis of Mycophenolic acid levels in pediatric transplant patients.  Pediatric Transplantation.  7s4:  46-132, 2003 abstract

Ugo, Kraus, Racusen, Haas, Burdick, Montgomery, Colombani, Lau, Paidas, Kling, Eustace, Zachary, Leffell, Reeb, Molmenti, Ratner, Samaniego, Rabb, Rodriquez-Reimunder, Molmenti.  Outcome of cadaveric pediatric renal allografts according to early recipient creatinine values:  extended and non-extended criteria organs.  Transplantation supp.  74:  705, 2002 abstract 3455

Falta, Kraus, Ugo, Racusen, Haas, Burdick, Montgomery, Colombani, Lau, Paidas, Kling, Eustace, Zachary, Leffell, Reeb, Molmenti, Ratner, Samaniego, Rabb, Molmenti.  Incidence of acute and chronic rejection in pediatric and adult cadaveric renal donors.  Transplantation supp.  74:  705, 2002 abstract 3456

Kling, Kirby, Kim, McFadden.  IL-10 decreases TNFa mRNA and protein in a necrotizing enterocolitis model.  AAS program.  31:  142, 1997 abstract 89

Kling, Rongione, Kwan, Mai, McFadden.  Bcl-2 overexpression is linked to pancreatic cancer resistance to chemotherapy.  SSO Cancer Symposium.  50:  46, 1997 abstract 46

Rongione, Kling, Zinner, Newton, Ashley, McFadden.  Intravenous growth factors stimulate glucose absorption through the luminal sodium/glucose cotransporter.  Surgical Forum.  82:  180, 1996

Kling, Kwan, Menon, Rongione, Ashley, McFadden.  Survival benefit in a neonatal rat model of necrotizing enterocolitis with IL-10.  Gastroenterology.  110:  1996 abstract 812

Kling, Rongione, McFadden.  Peptide YY growth inhibition of colon carcinoma.  Gastroenterology.  110:  1996 abstract 543

Rongione, Newton, Zinner, Kling, Ashley, McFadden.  Luminal growth factors enhance intestinal absorption of glucose, water, and electrolytes.  Gastroenterology.  110:  1996 abstract 835

Dunn, Lane, Rongione, Kling, Newton, Zinner, McFadden, Ashley.  Cholera toxin alters intestinal transport by neural mechanisms.  Gastroenterology.  110:  1996 abstract 322 

Book Chapters

Kling.  Congenital Pulmonary Anomalies.  In:  Baumgartner W, Yuh D, Vricella, L.  (eds)  The Johns Hopkins Manual of Cardiothoracic Surgery.  McGraw-Hill, New York : chapter ,

Kling.  Soft Tissue Injuries.  In:  Nichols, Lappe, Paidas, Yaster, Schleien.  (eds)  Golden Hour:  The Handbook of Advanced Pediatric Life Support.  3/e.  Elsevier, Philadelphia : chapter ,

Kling.  Pediatric Renal Transplantation.  In:  Oldham, Colombani, Foglia, Skinner.  (eds) Surgery of Infants and Children.  Lippincott Williams & Wilkins, Philadelphia 2004: chapter 47, 729-42

Kling, Colombani:  Surgical management of congenital lesions of the lung.  In:  Franco, Putnam.  (eds)  Advanced Therapy in Thoracic Surgery.  BC Decker Inc., Hamilton, ON :

Kling, Paidas.  Constipation and Incontinence.  In:  Mattei.  (ed)  Surgical Directives:  Pediatric Surgery.  Lippincott Williams & Wilkins, Philadelphia 2002: 363-70

Presentations

Kling.  Reduced Graft Techniques in Pediatric Liver Transplantation.  Invited speaker, University of Maryland Department of Surgery Grand Rounds/CME symposium in Honor of J. Laurance Hill, Baltimore, MD, 6/23/05

Kling.  Pediatric Transplantation.  Invited speaker, Pediatric Grand Rounds – Greater Baltimore Medical Center, Towson, MD, 3/17/05

Kling.  Pediatric Renal Transplantation.  Invited speaker, Johns Hopkins Immunogenetics Group, Baltimore, MD, 11/29/04

Kling.  Pediatric Liver and Kidney Transplantation.  Invited Hopkins Pediatric ICU lecture.  Baltimore, MD, 7/03

Kling, Lau, Colombani.  Outcome of vascular reconstruction in pediatric living related liver transplantation.  British Association of Paediatric Surgeons Annual Meeting, Estoril, Portugal, 7/03

Kling, Conner, Lau, Colombani, Cuffari.  Pharmacokinetic analysis of Mycophenolic acid levels in pediatric transplant patients.  International Pediatric Transplant Association 2nd Congress, Rio de Janeiro, Brazil, 4/03

Kling, Lau, Colombani.  Biliary complications of living related pediatric transplant patients. International Pediatric Transplant Association 2nd Congress, Rio de Janeiro, Brazil, 4/03

Kling, Applebaum, Dunn, Buchmiller, Atkinson.  Lateral Duodenectomy and Duodenostomy:  a novel technique for jejunal atresia near the ligament of Treitz.  invited vesalius.com presentation  11/99

Kling, Applebaum, Dunn, Buchmiller, Atkinson.  Lateral Duodenectomy and duodenostomy:  a novel technique for jejunal atresia near the ligament of Treitz.  APSA, Rancho Mirage, CA  5/99

Kling, Kirby, Kim, McFadden.  IL-10 decreases TNFa mRNA and protein in a necrotizing enterocolitis model.  AAS, Dallas, TX  11/97

Rigberg, Cole, Kling, Kim, Lane, McFadden.  p53 mutational status and chemoresistance in esophageal squamous cell carcinoma.  VA Surgeons, Louisville, KY  8/97

Kling, Cole, Rigberg, Kim, McFadden.  Peptide YY and apoptosis:  clues to chemotherapy resistance and colon cancer.  SSAT, Washington, DC  5/97

Kling, Kwan, McFadden.  bcl-2 overexpression is linked to pancreatic cancer resistance to chemotherapy.  SSO, Chicago, IL  3/97

Kling, Aharon, Thompson, Hiyama.  Video assisted thoracoscopic surgery as primary treatment for spontaneous pneumothorax.  Southern California ACS, Dana Point, CA  1/97

Kling, Schmit.  Breast conservation after induction chemotherapy for locally advanced breast cancer.  Southern California ACS, Dana Point, CA  1/97

Kling, Kwan, Rongione, Dunn, Ashley, McFadden.  Interleukin-10 (IL-10) treatment decreases iNOS expression in a necrotizing enterocolitis model.  AAS, Chicago, IL  11/96

Rongione, Kling, Zinner, Newton, Ashley, McFadden.  Intravenous growth factors stimulate glucose absorption through the luminal sodium/glucose cotransporter.  ACS, San Francisco, CA  10/96

Kling, McFadden.  Peptide YY and its analogs in gastrointestinal malignancies.  Gut Hormones.  Florissant, CO  7/96

Kling, Kwan, Menon, Rongione, Ashley, McFadden.  Survival benefit in a neonatal rat model of necrotizing enterocolitis with IL-10.  AGA, San Francisco, CA  5/96

Dunn, Lane, Rongione, Kling, Newton, Zinner, McFadden, Ashley.  Cholera toxin alters intestinal transport by neural mechanisms.  AGA, San Francisco, CA  5/96

Rongione, Newton, Zinner, Kling, Ashley, McFadden.  Luminal growth factors enhance intestinal absorption of glucose, water, and electrolytes.  AGA, San Francisco, CA  5/96

Kling, Mai, Kwan, Newton, Rongione, Ashley, McFadden.  PYY inhibits growth of human colon carcinoma in vitro.  Longmire Visiting lecture and research day, Los Angeles, CA  3/96

Kling, Rongione, Newton, Ashley, McFadden.  Short chain fatty acids mediate intestinal absorption.  SUS, Washington, DC  2/96

Kling, Rongione, Evans, McFadden.  The Delorme procedure:  a useful operation for complicated rectal prolapse in the elderly.  Southern California ACS, Santa Barbara, CA  1/96

Rongione, Evans, Kling, McFadden.  Ductography is a useful technique in evaluation of abnormal nipple discharge.  Southern California ACS, Santa Barbara, CA  1/96

Rongione, Kling, Evans, Ashley, McFadden.  Peptide YY:  A novel treatment for breast cancer.  Southern California ACS, Santa Barbara, CA  1/96

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